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Potential applications of porphyrins in photodynamic inactivation beyond the medical scope

Paper ID Volume ID Publish Year Pages File Format Full-Text
31302 44736 2015 24 PDF Available
Title
Potential applications of porphyrins in photodynamic inactivation beyond the medical scope
Abstract

•Photodynamic inactivation by porphyrins is efficient on microbes and other organisms.•It is efficient in water and food cleaning, control of insect pests and fish infections.•It may be used to disinfect surfaces, objects or materials in a self-cleaning way.•The use of sunlight provides cost-effectiveness in relation to the light source.•Natural porphyrins or synthetically accessible compounds are also cost-effective.

Although the discovery of light-activated antimicrobial agents had been reported in the 1900s, only more recently research work has been developed toward the use of photodynamic process as an alternative to more conventional methods of inactivation of micro(organisms). The photoprocess causes cell death through irreversible oxidative damage by reactive oxygen species produced by the interaction between a photosensitizing compound and a light source.With great emphasis on the environmental area, photodynamic inactivation (PDI) has been tested in insect eradication and in water disinfection. Lately, other studies have been carried out concerning its possible use in aquaculture waters or to the control of food-borne pathogens. Other potential applications of PDI in household, industrial and hospital settings have been considered.In the last decade, scientific research in this area has gained importance not only due to great developments in the field of materials chemistry but also because of the serious problem of the increasing number of bacterial species resistant to common antibiotics. In fact, the design of antimicrobial surfaces or self-cleaning materials is a very appealing idea from the economic, social and public health standpoints. Thus, PDI of micro(organisms) represents a promising alternative.In this review, the efforts made in the last decade in the investigation of PDI of (micro)organisms with potential applications beyond the medical field will be discussed, focusing on porphyrins, free or immobilized on solid supports, as photosensitizing agents.

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Keywords
Porphyrin; Photosensitizer; Photodynamic inactivation; Disinfection; Nanomaterials; Self-cleaning materials
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Publisher
Database: Elsevier - ScienceDirect
Journal: Journal of Photochemistry and Photobiology C: Photochemistry Reviews - Volume 22, March 2015, Pages 34–57
Authors
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Subjects
Physical Sciences and Engineering Chemical Engineering Bioengineering
Get Full-Text Now
Don't Miss Today's Special Offer
Price was $35.95
You save - $31
Price after discount Only $4.95
100% Money Back Guarantee
Full-text PDF Download
Online Support
Any Questions? feel free to contact us