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Application and engineering of fatty acid biosynthesis in Escherichia coli for advanced fuels and chemicals

Paper ID Volume ID Publish Year Pages File Format Full-Text
31832 44842 2011 10 PDF Available
Title
Application and engineering of fatty acid biosynthesis in Escherichia coli for advanced fuels and chemicals
Abstract

Research towards the commercialization of fungible biofuels has received a great deal of recent interest and investment. To this end the microbial production of fatty acid-derived fuels from sustainable feedstocks is emerging as a viable option with rapid advances from both industry and academia. The manipulation of the fatty acid biosynthesis pathway, especially in Escherichia coli, has been widely studied and several approaches that increase fatty acid production have been identified. However, further advances will be required for the economic large-scale production of fatty acid-derived biofuels. Here we present an overview of fatty acid biosynthesis and its regulation in E. coli from a metabolic engineering viewpoint and offer potential approaches and considerations for the microbial overproduction of custom designed fatty acids for use as biofuels or in the manufacture of oleochemicals.

Keywords
Fatty acid; Biofuel; Diesel; Metabolic engineering; Escherichia coli
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Application and engineering of fatty acid biosynthesis in Escherichia coli for advanced fuels and chemicals
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Publisher
Database: Elsevier - ScienceDirect
Journal: Metabolic Engineering - Volume 13, Issue 1, January 2011, Pages 28–37
Authors
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Subjects
Physical Sciences and Engineering Chemical Engineering Bioengineering
Get Full-Text Now
Don't Miss Today's Special Offer
Price was $35.95
You save - $31
Price after discount Only $4.95
100% Money Back Guarantee
Full-text PDF Download
Online Support
Any Questions? feel free to contact us