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Triggered nanoparticles as therapeutics

Paper ID Volume ID Publish Year Pages File Format Full-Text
32096 44899 2013 9 PDF Available
Title
Triggered nanoparticles as therapeutics
Abstract

•Triggered nanoparticles provide therapeutic benefits.•Exogenously mediated release of therapeutics from nanoparticle surfaces using external stimuli is discussed.•Endogenously mediated release using environmental differences in living systems is overviewed.•Developing multifunctional nanoparticles allows for theragnostic applications.

SummaryDrug delivery systems (DDSs) face several challenges including site-specific delivery, stability, and the programmed release of drugs. Engineered nanoparticle (NP) surfaces with responsive moieties can enhance the efficacy of DDSs for in vitro and in vivo systems. This triggering process can be achieved through both endogenous (biologically controlled release) and exogenous (external stimuli controlled release) activation. In this review, we will highlight recent examples of the use of triggered release strategies of engineered nanomaterials for in vitro and in vivo applications.

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Keywords
Engineered nanoparticles; Drug delivery system; In vitro; In vivo; Triggered release
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Triggered nanoparticles as therapeutics
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Publisher
Database: Elsevier - ScienceDirect
Journal: - Volume 8, Issue 4, August 2013, Pages 439–447
Authors
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Subjects
Physical Sciences and Engineering Chemical Engineering Bioengineering
Get Full-Text Now
Don't Miss Today's Special Offer
Price was $35.95
You save - $31
Price after discount Only $4.95
100% Money Back Guarantee
Full-text PDF Download
Online Support
Any Questions? feel free to contact us