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Advances in nanofibrous scaffolds for biomedical applications: From electrospinning to self-assembly

Paper ID Volume ID Publish Year Pages File Format Full-Text
32129 44902 2014 21 PDF Available
Title
Advances in nanofibrous scaffolds for biomedical applications: From electrospinning to self-assembly
Abstract

•Natural extracellular matrix structure motivates the use of nanofibrous materials.•Techniques for creating nanofibrous scaffolds are discussed in detail.•Emphasis is placed on electrospinning, phase separation, and self-assembly.•Examples are provided of recent advances in applications of nanofibrous scaffolds.

SummaryIncreased understanding of the nanoscale structural features of the extracellular matrix (ECM) in directing cell and tissue function has led to the development of materials with nanofibrous architectures to mimic the biophysical cues of natural ECM. This review briefly discusses the importance of structural features within ECM and then examines the techniques that researchers have developed to recreate these structural features in materials. In particular, techniques including electrospinning, phase separation, and self-assembly are discussed in detail for their ability to fabricate nanofibrous scaffolds with various chemical and structural features. Advances in biomedical applications of nanofibrous scaffolds are highlighted with a particular focus on more recent studies to illustrate the current state of the field.

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Keywords
Nanofibers; Tissue engineering; Biomaterials; Electrospinning; Self-assembly; Phase separation
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Advances in nanofibrous scaffolds for biomedical applications: From electrospinning to self-assembly
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Publisher
Database: Elsevier - ScienceDirect
Journal: - Volume 9, Issue 6, December 2014, Pages 722–742
Authors
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Subjects
Physical Sciences and Engineering Chemical Engineering Bioengineering
Get Full-Text Now
Don't Miss Today's Special Offer
Price was $35.95
You save - $31
Price after discount Only $4.95
100% Money Back Guarantee
Full-text PDF Download
Online Support
Any Questions? feel free to contact us