fulltext.study @t Gmail

Lanthanide-doped up-converting nanoparticles: Merits and challenges

Paper ID Volume ID Publish Year Pages File Format Full-Text
32151 44905 2012 32 PDF Available
Title
Lanthanide-doped up-converting nanoparticles: Merits and challenges
Abstract

SummaryDue to exceptional photo-physical properties, up-converting nanoparticles (UCNPs) are promising and advantageous alternative to conventional fluorescent labels used in many bio-medical applications. The first part of this review aims at presenting these properties as well as the current state-of-the-art in the up-conversion enhancement, NPs surface functionalization and bioconjugation. In the second part of the paper, the applications of UCNPs and currently available detection instrumentation are discussed in the view of the distinctive properties of these markers. Because the growing widespread use of the biofunctionalized NPs, scarce instrumentation for up-conversion detection is reviewed. Finally, the challenges and future perspectives of the UCNPs are discussed.

Graphical abstractFigure optionsDownload full-size imageDownload high-quality image (187 K)Download as PowerPoint slideHighlights► Lanthanide up-conversion nanoparticles (Ln:UCNPs) offer significant advantages over traditionally used biolabels. ► With the use of UCNPs, bioimaging and biosensing gains higher sensitivity, photostability, optical resolution and measurement simplicity. ► Up-conversion enhancement, novel up-converting nanomaterials and nanoparticle architectures require further optimization. ► Lack of dedicated instrumentation limits the broader widespread use of this promising technology.

Keywords
AHA, 6-aminohexanoic acid; AF, autoflorescence; APTE, (fr.) Addition de Photons par Transferts d’Energie; APTES, 3-aminopropyltriethoxysilane; APTMS, 3-aminopropyltrimethoxysilane; CL, cooperative luminescence; CS, cooperative sensitization; EDC, 1-ethyl-
First Page Preview
Lanthanide-doped up-converting nanoparticles: Merits and challenges
Get Full-Text Now
Don't Miss Today's Special Offer
Price was $35.95
You save - $31
Price after discount Only $4.95
100% Money Back Guarantee
Full-text PDF Download
Online Support
Any Questions? feel free to contact us
Publisher
Database: Elsevier - ScienceDirect
Journal: - Volume 7, Issue 6, December 2012, Pages 532–563
Authors
, ,
Subjects
Physical Sciences and Engineering Chemical Engineering Bioengineering
Get Full-Text Now
Don't Miss Today's Special Offer
Price was $35.95
You save - $31
Price after discount Only $4.95
100% Money Back Guarantee
Full-text PDF Download
Online Support
Any Questions? feel free to contact us