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Polymeric nanomedicines for image-guided drug delivery and tumor-targeted combination therapy

Paper ID Volume ID Publish Year Pages File Format Full-Text
32363 44924 2010 16 PDF Available
Title
Polymeric nanomedicines for image-guided drug delivery and tumor-targeted combination therapy
Abstract

SummaryNanomedicine systems aim to improve the biodistribution and the target site accumulation of systemically applied (chemo-) therapeutics. By increasing drug localization at the pathological site, and by reducing its accumulation in healthy organs and tissues, the efficacy of the intervention can often be increased, while its toxicity can be attenuated. Using HPMA copolymers as a model macromolecular nanomedicine system, and several selected examples of recently published proof-of-principle reports, we here show that besides for standard drug delivery purposes, polymeric nanomedicines can also be employed for image-guided drug delivery, as well as for tumor-targeted combination therapy.

Keywords
Nanomedicines; Drug targeting; Polymer therapeutics; Image-guided drug delivery; Theranostics; Combination therapy
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Polymeric nanomedicines for image-guided drug delivery and tumor-targeted combination therapy
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Publisher
Database: Elsevier - ScienceDirect
Journal: - Volume 5, Issue 3, June 2010, Pages 197–212
Authors
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Subjects
Physical Sciences and Engineering Chemical Engineering Bioengineering
Get Full-Text Now
Don't Miss Today's Special Offer
Price was $35.95
You save - $31
Price after discount Only $4.95
100% Money Back Guarantee
Full-text PDF Download
Online Support
Any Questions? feel free to contact us