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Multifunctional quantum dots for personalized medicine

Paper ID Volume ID Publish Year Pages File Format Full-Text
32378 44925 2009 15 PDF Available
Title
Multifunctional quantum dots for personalized medicine
Abstract

SummarySuccesses in biomedical research and state-of-the-art medicine have undoubtedly improved the quality of life. However, a number of diseases, such as cancer, immunodeficiencies, and neurological disorders, still evade conventional diagnostic and therapeutic approaches. A transformation towards personalized medicine may help to combat these diseases. For this, identification of disease molecular fingerprints and their association with prognosis and targeted therapy must become available. Quantum dots (QDs), semiconductor nanocrystals with unique photo-physical properties, represent a novel class of fluorescence probes to address many of the needs of personalized medicine. This review outlines the properties of QDs that make them a suitable platform for advancing personalized medicine, examines several proof-of-concept studies showing utility of QDs for clinically relevant applications, and discusses current challenges in introducing QDs into clinical practice.

Keywords
Quantum dots; Nanoparticles; Molecular profiling; Fluorescence; Multiplexing; Pathology; Diagnosis; Targeted therapy; Drug delivery; Personalized medicine
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Multifunctional quantum dots for personalized medicine
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Publisher
Database: Elsevier - ScienceDirect
Journal: - Volume 4, Issue 5, October 2009, Pages 414–428
Authors
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Subjects
Physical Sciences and Engineering Chemical Engineering Bioengineering
Get Full-Text Now
Don't Miss Today's Special Offer
Price was $35.95
You save - $31
Price after discount Only $4.95
100% Money Back Guarantee
Full-text PDF Download
Online Support
Any Questions? feel free to contact us