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Influence of nanoscale surface topography on protein adsorption and cellular response

Paper ID Volume ID Publish Year Pages File Format Full-Text
32511 44933 2010 13 PDF Available
Title
Influence of nanoscale surface topography on protein adsorption and cellular response
Abstract

The nanoscale surface topography of artificial materials is known to play a significant role in interactions with biological systems such as proteins and cells. A detailed understanding, and ultimately control, of these interactions is therefore of utmost importance in areas such as cell culture technology, biosensing and medical device development. We briefly review different methods to synthesise and fabricate surfaces with well-defined nanoscale topography, and discuss how such nanostructured surfaces can be used as model systems in protein and cellular assays. Finally, an outlook of possible future in vitro and in vivo developments is provided.

Keywords
Nanoscale surface topography (nanotopography); Protein adsorption; Cellular response
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Publisher
Database: Elsevier - ScienceDirect
Journal: - Volume 5, Issue 1, February 2010, Pages 66–78
Authors
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Subjects
Physical Sciences and Engineering Chemical Engineering Bioengineering
Get Full-Text Now
Don't Miss Today's Special Offer
Price was $35.95
You save - $31
Price after discount Only $4.95
100% Money Back Guarantee
Full-text PDF Download
Online Support
Any Questions? feel free to contact us