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Designer self-assembling peptide nanomaterials

Paper ID Volume ID Publish Year Pages File Format Full-Text
32563 44935 2009 18 PDF Available
Title
Designer self-assembling peptide nanomaterials
Abstract

SummaryShort peptides that are made of natural amino acids were never seriously considered as useful materials as recent as 16 years ago. However, the discovery of a class of self-assembling peptides that spontaneously undergo self-organization into well-ordered structures resulted in a conceptual change. Since then diverse classes of short peptides have been invented with broad applications including 3D tissue cell culture, reparative and regenerative medicine, tissue engineering, slow drug release, stabilization of membrane proteins to develop nanobiotechnology and molecular devices. Furthermore one of the self-assembling peptides has shown promise not only to slow down prion infection, but also to extend ∼50% animal life. Molecular design using short peptides as new materials may play increasingly important role in nanoscience, nanotechnology, nanobiotechnology and nanomedicine.

Keywords
3D cell cultures; Ionic self-complementary peptides; Lipid-like peptides; Molecular self-assembly; Stabilizing membrane proteins; Tissue regeneration
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Designer self-assembling peptide nanomaterials
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Publisher
Database: Elsevier - ScienceDirect
Journal: - Volume 4, Issue 2, April 2009, Pages 193–210
Authors
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Subjects
Physical Sciences and Engineering Chemical Engineering Bioengineering
Get Full-Text Now
Don't Miss Today's Special Offer
Price was $35.95
You save - $31
Price after discount Only $4.95
100% Money Back Guarantee
Full-text PDF Download
Online Support
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