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Biomedical nanoparticle carriers with combined thermal and magnetic responses

Paper ID Volume ID Publish Year Pages File Format Full-Text
32667 44939 2009 14 PDF Available
Title
Biomedical nanoparticle carriers with combined thermal and magnetic responses
Abstract

SummarySeveral biocompatible polymers are capable of large responses to small temperature changes around 37 °C. In water, their responses include shrinkage and swelling as well as transitions in wettability. These properties have been harnessed for biomedical applications such as tissue engineering scaffolds and drug delivery carriers. A soft material/hard material hybrid in which a magnetic metal or oxide is embedded in a temperature-responsive polymer matrix can combine the thermal sensitivity with magnetic signatures. Importantly, nanosizing such construct brings about new desirable features of extremely fast thermal response time, small magnetic hysteresis and enhanced magnetic susceptibility. Remote magnetic maneuvering and heating of the hybrid nanocolloids makes possible such applications as high-throughput enzyme separation and cell screening. Robust drug release on demand may also be obtained using these colloids and nanoparticle-derived thin film devices of combined thermal magnetic sensitivity.

Keywords
Nanoparticles; Biomedical; Thermal response; Magnetic response; Drug delivery
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Biomedical nanoparticle carriers with combined thermal and magnetic responses
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Publisher
Database: Elsevier - ScienceDirect
Journal: - Volume 4, Issue 1, February 2009, Pages 52–65
Authors
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Subjects
Physical Sciences and Engineering Chemical Engineering Bioengineering
Get Full-Text Now
Don't Miss Today's Special Offer
Price was $35.95
You save - $31
Price after discount Only $4.95
100% Money Back Guarantee
Full-text PDF Download
Online Support
Any Questions? feel free to contact us