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Self-assembled polymer nanostructures for delivery of anticancer therapeutics

Paper ID Volume ID Publish Year Pages File Format Full-Text
32738 44942 2009 16 PDF Available
Title
Self-assembled polymer nanostructures for delivery of anticancer therapeutics
Abstract

Nanostructures self-assembled from amphiphilic functional copolymers have emerged as safe and efficient nanocarriers for delivery of anticancer therapeutics. The development of this class of nanostructures has advanced from basic spherical micelles for delivery of small molecular hydrophobic drugs to a more complex functional structure for more efficient delivery of a wide range of therapeutics including small molecular drugs, macromolecular proteins and genes. This review describes physiological barriers for delivery of therapeutics, summarizes various approaches to overcome these barriers, and discusses the challenges in the current approaches for cancer therapy and perspectives for future solutions.

Keywords
Self-assembly; Polymer nanostructures; Drug delivery; Protein delivery; Gene delivery; Cancer therapy
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Self-assembled polymer nanostructures for delivery of anticancer therapeutics
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Publisher
Database: Elsevier - ScienceDirect
Journal: - Volume 4, Issue 4, August 2009, Pages 302–317
Authors
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Subjects
Physical Sciences and Engineering Chemical Engineering Bioengineering
Get Full-Text Now
Don't Miss Today's Special Offer
Price was $35.95
You save - $31
Price after discount Only $4.95
100% Money Back Guarantee
Full-text PDF Download
Online Support
Any Questions? feel free to contact us