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Synthesis and biomedical applications of hollow nanostructures

Paper ID Volume ID Publish Year Pages File Format Full-Text
32742 44942 2009 15 PDF Available
Title
Synthesis and biomedical applications of hollow nanostructures
Abstract

SummaryHollow nanostructures have attracted tremendous attention from researchers in various disciplines because their high surface to volume ratio and large pore volume are highly desirable for many technological applications including drug delivery system. Several colloidal synthetic methods have been used to synthesize various hollow nanostructures. These synthetic approaches are mainly categorized into four main classes according to how the hollow structure is formed: the Kirkendall effect, chemical etching, galvanic replacement, and template-mediated approach. The large pores inside the hollow nanostructures can encapsulate and release various drugs and biomolecules, while the surface of the nanostructure can be functionalized for drug targeting or bio-labeling. These features make the hollow nanostructures a unique and promising candidate as multifunctional drug delivery vehicles. This review article covers recent progress concerning the synthesis of hollow nanostructures with their sizes smaller than 200 nm and their biomedical applications including specific targeting, imaging, and controlled release of therapeutics for simultaneous diagnosis and therapy.

Keywords
Hollow; Nanoparticle; Kirkendall effect; Galvanic replacement; Etching; Biomedical applications; Template synthesis; Drug delivery vehicle
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Synthesis and biomedical applications of hollow nanostructures
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Publisher
Database: Elsevier - ScienceDirect
Journal: - Volume 4, Issue 4, August 2009, Pages 359–373
Authors
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Subjects
Physical Sciences and Engineering Chemical Engineering Bioengineering
Get Full-Text Now
Don't Miss Today's Special Offer
Price was $35.95
You save - $31
Price after discount Only $4.95
100% Money Back Guarantee
Full-text PDF Download
Online Support
Any Questions? feel free to contact us