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Cell-free protein synthesis: applications in proteomics and biotechnology

Paper ID Volume ID Publish Year Pages File Format Full-Text
33925 44998 2008 7 PDF Available
Title
Cell-free protein synthesis: applications in proteomics and biotechnology
Abstract

Protein production is one of the key steps in biotechnology and functional proteomics. Expression of proteins in heterologous hosts (such as in E. coli) is generally lengthy and costly. Cell-free protein synthesis is thus emerging as an attractive alternative. In addition to the simplicity and speed for protein production, cell-free expression allows generation of functional proteins that are difficult to produce by in vivo systems. Recent exploitation of cell-free systems enables novel development of technologies for rapid discovery of proteins with desirable properties from very large libraries. This article reviews the recent development in cell-free systems and their application in the large scale protein analysis.

First Page Preview
Cell-free protein synthesis: applications in proteomics and biotechnology
Publisher
Database: Elsevier - ScienceDirect
Journal: New Biotechnology - Volume 25, Issues 2–3, October–December 2008, Pages 126–132
Authors
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Subjects
Physical Sciences and Engineering Chemical Engineering Bioengineering