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Butyric acid production with Clostridium tyrobutyricum immobilised to PVA gel

Paper ID Volume ID Publish Year Pages File Format Full-Text
34176 45008 2016 5 PDF Available
Title
Butyric acid production with Clostridium tyrobutyricum immobilised to PVA gel
Abstract

•Immobilisation of Clostridium tyrobutyricum to PVA gel.•Remarkable stability of microorganism in repeated batches and continuous fermentations.•Improvement of productivity of immobilised cell.•Evaluation of entrapment and adsorption of biomass in/on PVA particles.

Clostridium tyrobutyricum was entrapped into lens-shaped polyvinyl alcohol particles (LentiKats®). Immobilised cells were propagated in series of repeated batches and reached average productivity of 1.74 g/L h and yield of 0.44 g/g during 31 repetitions with glucose as an initial substrate, which was 5 times higher productivity compared with a free cell system under the same conditions. Immobilised cells were successfully applied for more than 71 repeated batches and demonstrated remarkable process stability. Application of immobilised cells to a continuous system resulted in 5.8 times higher productivity compared with free cells, with 6.8 g/L of butyric acid and residual glucose of 5.8 g/L.

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Keywords
Clostridium tyrobutyricum; Butyric acid; Immobilisation; LentiKats®
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Publisher
Database: Elsevier - ScienceDirect
Journal: Process Biochemistry - Volume 51, Issue 6, June 2016, Pages 704–708
Authors
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Subjects
Physical Sciences and Engineering Chemical Engineering Bioengineering
Get Full-Text Now
Don't Miss Today's Special Offer
Price was $35.95
You save - $31
Price after discount Only $4.95
100% Money Back Guarantee
Full-text PDF Download
Online Support
Any Questions? feel free to contact us