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Enzymatically enriching naringenin with hydroxylated and/or methoxylated phenolic compounds

Paper ID Volume ID Publish Year Pages File Format Full-Text
34891 45056 2011 6 PDF Available
Title
Enzymatically enriching naringenin with hydroxylated and/or methoxylated phenolic compounds
Abstract

The demand for supplementary dietary antioxidants is increasing as their role in preventing oxidative stress is becoming clearer. This study was therefore aimed at investigating the possibility of coupling simple phenolic molecules rich in hydroxyl groups and/or methoxyl groups onto naringenin by using laccases in order to enhance its antioxidant activity. In all cases, up to two catechol, guaiacol, ferulic and sinapic acid molecules were covalently coupled onto naringenin. The type of solvent used had an impact of coupling efficiencies with highest yields obtained for ethyl acetate when compared to methanol and acetonitrile. Proposed coupling structures predominantly showed a C–C bonding except for sinapic acid which was bound through 4-O-5 coupling. Indeed an increase in hydroxyl groups and/or methoxyl groups, which may positively influence antioxidant activities, was inferred from the chromatographic and mass data.

Keywords
Naringenin; Laccase; Coupling; Antioxidants; Reactive species
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Enzymatically enriching naringenin with hydroxylated and/or methoxylated phenolic compounds
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Publisher
Database: Elsevier - ScienceDirect
Journal: Process Biochemistry - Volume 46, Issue 4, April 2011, Pages 1019–1024
Authors
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Subjects
Physical Sciences and Engineering Chemical Engineering Bioengineering
Get Full-Text Now
Don't Miss Today's Special Offer
Price was $35.95
You save - $31
Price after discount Only $4.95
100% Money Back Guarantee
Full-text PDF Download
Online Support
Any Questions? feel free to contact us