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Evaluation of solid phase extraction for downstream separation of propane-1,3-diol and butan-1-ol from fermentation broth

Paper ID Volume ID Publish Year Pages File Format Full-Text
35157 45078 2012 6 PDF Available
Title
Evaluation of solid phase extraction for downstream separation of propane-1,3-diol and butan-1-ol from fermentation broth
Abstract

Today, glycerol is mainly a by-product of fat splitting and biodiesel production. This study examined the use of chemically modified silica gels for downstream separation of propane-1,3-diol and butan-1-ol from fermentation broths obtained through the glycerol fermentation process. The developed method was found to be simple and efficient for the isolation and purification of butan-1-ol from the other components in the fermentation mixture. However, in the case of the separation of propane-1,3-diol from fermentation broth, the silica gel sorbents were ineffective.

► The study is based on the actual fermentation broths. ► The influence of cell debris, proteins and nutrients is reflected in the results. ► The most promising modified silica gels are selected for butanol separation. ► The separation of PDO by modified silica gels was excluded. ► The composition of glycerol based fermentation broths was presented.

Keywords
Propane-1,3-diol; Butan-1-ol; Glycerol; Chromatography; Downstream separation
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Evaluation of solid phase extraction for downstream separation of propane-1,3-diol and butan-1-ol from fermentation broth
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Publisher
Database: Elsevier - ScienceDirect
Journal: Process Biochemistry - Volume 47, Issue 6, June 2012, Pages 1005–1010
Authors
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Subjects
Physical Sciences and Engineering Chemical Engineering Bioengineering
Get Full-Text Now
Don't Miss Today's Special Offer
Price was $35.95
You save - $31
Price after discount Only $4.95
100% Money Back Guarantee
Full-text PDF Download
Online Support
Any Questions? feel free to contact us