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Variation in the ginsenoside profiles of cultivated ginseng (Panax ginseng C.A. Meyer) landraces in Korea

Paper ID Volume ID Publish Year Pages File Format Full-Text
35384 45088 2011 7 PDF Available
Title
Variation in the ginsenoside profiles of cultivated ginseng (Panax ginseng C.A. Meyer) landraces in Korea
Abstract

Heterogeneity of ginsenosides is a remarkable and significant issue because those structure-similar secondary metabolites have different or even totally opposite pharmacological activities. This study describes ginsenoside profile variations in Panax ginseng C.A. Meyer cultivated in Korea using an HPLC-UV coupled to ESI-MS for characterization and quantification of ginsenosides contained in the root of ginseng. The [M-H]− ion was observed for ginsenoside standards (Rg1, Re, Rf, Rh1, Rg2, Rb1, Rc, Rb2, Rb3, Rd, Rg3 and Rh2) and 190 different ginseng extracts. The individual variations in the P. ginseng population were classified into three types, based on the expression pattern of six core ginsenosides containing Ra1/Ra2 and malonyl-Ra1/Ra2 isomers. The variations in the six core ginsenosides, which are defined as pattern indicators, play a key role in discriminating between three subtypes of standard P. ginseng species. In addition, cross-correlation analysis of the identified ginsenosides indicates that the specific ginsenosides, including pattern-indicating components, are in part possibly synthesized via common ginsenoside biosynthesis pathways. Taken together, these findings provide a basis for identifying standard P. ginseng landraces.

Keywords
Panax ginseng; Ginsenosides; Chromatographic pattern; Pattern indicators; Ra1/Ra2 isomer
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Variation in the ginsenoside profiles of cultivated ginseng (Panax ginseng C.A. Meyer) landraces in Korea
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Publisher
Database: Elsevier - ScienceDirect
Journal: Process Biochemistry - Volume 46, Issue 1, January 2011, Pages 258–264
Authors
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Subjects
Physical Sciences and Engineering Chemical Engineering Bioengineering
Get Full-Text Now
Don't Miss Today's Special Offer
Price was $35.95
You save - $31
Price after discount Only $4.95
100% Money Back Guarantee
Full-text PDF Download
Online Support
Any Questions? feel free to contact us