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Design and analysis of poly-3-hydroxybutyrate production processes from crude glycerol

Paper ID Volume ID Publish Year Pages File Format Full-Text
35392 45088 2011 8 PDF Available
Title
Design and analysis of poly-3-hydroxybutyrate production processes from crude glycerol
Abstract

The growing biodiesel production has generated a glycerol surplus and consequently a drop of its sale price. The development of biorefineries to convert crude glycerol to higher value products is an urgent need and an opportunity to overcome the negative impact of low glycerol prices in the biodiesel industry. Glycerol fermentation by microorganisms to useful chemicals as poly-3-hydroxybutyrate (PHB) is an interesting alternative. In this article a techno-economical analysis for PHB production from crude glycerol is presented. The glycerol fermentation process was carried out using two qualities of glycerol, either 88 or 98 wt%. Thus, the glycerol purification process was simulated and economically analyzed using Aspen Plus and Aspen Icarus, respectively. The fermentation process is carried out in two stages in which mass cell growth and PHB accumulation occurs, respectively. Also, three downstream processes to isolate and purify the PHB were considered. The process steps, namely mass cell pretreatment, PHB isolation and purification were considered in each scenario and six technological schemes were analyzed. Economical assessment results show that the most appropriate technological scheme requires purifying the crude glycerol until 98 wt%, with a downstream process involving heat pretreatment, enzymatic-alkaline digestion, centrifugation, washing, evaporation, and spray drying.

Keywords
Glycerol purification; Glycerol bioconversion; PHB bioproduction; Process simulation; Process assessment; Economic assessment
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Design and analysis of poly-3-hydroxybutyrate production processes from crude glycerol
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Publisher
Database: Elsevier - ScienceDirect
Journal: Process Biochemistry - Volume 46, Issue 1, January 2011, Pages 310–317
Authors
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Subjects
Physical Sciences and Engineering Chemical Engineering Bioengineering
Get Full-Text Now
Don't Miss Today's Special Offer
Price was $35.95
You save - $31
Price after discount Only $4.95
100% Money Back Guarantee
Full-text PDF Download
Online Support
Any Questions? feel free to contact us