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Short-cut calculations for integrated product recovery options in fermentative production of bio-bulk chemicals

Paper ID Volume ID Publish Year Pages File Format Full-Text
35502 45093 2010 11 PDF Available
Title
Short-cut calculations for integrated product recovery options in fermentative production of bio-bulk chemicals
Abstract

Microorganisms are generally sensitive to high concentrations of products that they excrete. Such product inhibition and toxicity effects can significantly be reduced by the integration of fermentations with separation technologies to remove the products continuously. Cost-calculations are required to select the preferred integration method. This paper presents a shortcut calculation method that provides easy interpretable results to assist the reader in making rational design choices. The method distinguishes four main cost categories, being capital and operational expenditure for both fermentation and product recovery. We have applied these cost correlations to the production of three typical bio-based bulk chemicals. The results show the origin of the most significant costs in the investigated integrated bio-processes. The presented method can be used to direct future research efforts and might assist in evaluating the impact of integrated product recovery techniques on total production costs of bio-chemicals.

Keywords
Integrated product recovery; Lactic acid; Butanol; Phenol; Review; Cost calculations; Fermentation; Separation technology
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Short-cut calculations for integrated product recovery options in fermentative production of bio-bulk chemicals
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Publisher
Database: Elsevier - ScienceDirect
Journal: Process Biochemistry - Volume 45, Issue 10, October 2010, Pages 1605–1615
Authors
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Subjects
Physical Sciences and Engineering Chemical Engineering Bioengineering
Get Full-Text Now
Don't Miss Today's Special Offer
Price was $35.95
You save - $31
Price after discount Only $4.95
100% Money Back Guarantee
Full-text PDF Download
Online Support
Any Questions? feel free to contact us