fulltext.study @t Gmail

Development of a continuous cell-recycle fermentation system for production of lactic acid by Lactobacillus paracasei

Paper ID Volume ID Publish Year Pages File Format Full-Text
35942 45115 2006 6 PDF Available
Title
Development of a continuous cell-recycle fermentation system for production of lactic acid by Lactobacillus paracasei
Abstract

Experimental devices for stimulating productivity of lactic acid fermentation were installed and an electromagnetic flow-meter and a pneumatic diaphragm pump were employed to alleviate the fouling of the membrane and to improve the durability of membrane cell-recycle bioreactors (MCRBs). In this case, the continuous fermentation using a 5 L automatic fermentor lasted stably over 150 h, and could repeat periodically with simple intermittent on-line cleaning and sterilization of the membrane filtration system. Maximum value of OD620 of 98.7 was obtained, six times greater than that of the fed-batch fermentation. Meanwhile, maximum productivity of 31.5 g/(L h) was recorded, 10 times greater than that occurred in the fed-batch fermentation. Compared with conventional MCRBs, the MCRB system with a diaphragm pump and tangential flow-rate controlling was more stable and durable. The tangential velocity of membrane module could be monitored and controlled on-line, and the possibility of contamination due to hose rupture could be eliminated.

Keywords
Electromagnetic flow-meter; Lactobacillus paracasei; Lactic acid; Tangential velocity; Membrane bioreactor; Cell-recycle
First Page Preview
Development of a continuous cell-recycle fermentation system for production of lactic acid by Lactobacillus paracasei
Get Full-Text Now
Don't Miss Today's Special Offer
Price was $35.95
You save - $31
Price after discount Only $4.95
100% Money Back Guarantee
Full-text PDF Download
Online Support
Any Questions? feel free to contact us
Publisher
Database: Elsevier - ScienceDirect
Journal: Process Biochemistry - Volume 41, Issue 12, December 2006, Pages 2458–2463
Authors
, , , , , ,
Subjects
Physical Sciences and Engineering Chemical Engineering Bioengineering
Get Full-Text Now
Don't Miss Today's Special Offer
Price was $35.95
You save - $31
Price after discount Only $4.95
100% Money Back Guarantee
Full-text PDF Download
Online Support
Any Questions? feel free to contact us