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Effects of fluid dynamic induced shear stress on fungal growth and morphology

Paper ID Volume ID Publish Year Pages File Format Full-Text
36257 45126 2006 5 PDF Available
Title
Effects of fluid dynamic induced shear stress on fungal growth and morphology
Abstract

Industrial applications of filamentous microorganisms become more and more relevant for example for the production of pharmaceuticals. Therefore, pellet morphology is often requested. Knowledge about pellet growth behaviour at different fluid dynamic conditions is important, because many production processes are influenced by morphology. Morphology itself is influenced by the fluid dynamic conditions in a bioreactor. In the present study, pellet growth of Aspergillus niger AB1.13 was studied under different fluid dynamic conditions. A new experimental set-up was designed to guarantee comparability and reproducibility. Kinetic parameters of pellet growth were correlated with energy input and the maximum shear rate.The present work shows that kinetic parameters depend on the fluid dynamic conditions. Additionally, it could be demonstrated that for model development a correlation with the local maximum shear rate is of relevance especially in relation to transferability to other reaction systems with different set-up.

Keywords
Filamentous fungi; Fluid dynamic stress; Growth kinetics; Shear rate; Submerged culture
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Publisher
Database: Elsevier - ScienceDirect
Journal: Process Biochemistry - Volume 41, Issue 10, October 2006, Pages 2113–2117
Authors
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Subjects
Physical Sciences and Engineering Chemical Engineering Bioengineering
Get Full-Text Now
Don't Miss Today's Special Offer
Price was $35.95
You save - $31
Price after discount Only $4.95
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