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Bioprinting for cancer research

Paper ID Volume ID Publish Year Pages File Format Full-Text
36786 45266 2015 10 PDF Available
Title
Bioprinting for cancer research
Abstract

•Bioprinting techniques can be used to create 3D tumor models for cancer research.•Bioprinting methods include inkjet, microextrusion, and laser technologies.•3D cancer models mimic the tumor microenvironment better than 2D models.•This will lead to a better understanding of cancer and aid in cancer drug screening.

Bioprinting offers the ability to create highly complex 3D architectures with living cells. This cutting-edge technique has significantly gained popularity and applicability in several fields. Bioprinting methods have been developed to effectively and rapidly pattern living cells, biological macromolecules, and biomaterials. These technologies hold great potential for applications in cancer research. Bioprinted cancer models represent a significant improvement over previous 2D models by mimicking 3D complexity and facilitating physiologically relevant cell–cell and cell–matrix interactions. Here we review bioprinting methods based on inkjet, microextrusion, and laser technologies and compare 3D cancer models with 2D cancer models. We discuss bioprinted models that mimic the tumor microenvironment, providing a platform for deeper understanding of cancer pathology, anticancer drug screening, and cancer treatment development.

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Publisher
Database: Elsevier - ScienceDirect
Journal: - Volume 33, Issue 9, September 2015, Pages 504–513
Authors
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Subjects
Physical Sciences and Engineering Chemical Engineering Bioengineering
Get Full-Text Now
Don't Miss Today's Special Offer
Price was $35.95
You save - $31
Price after discount Only $4.95
100% Money Back Guarantee
Full-text PDF Download
Online Support
Any Questions? feel free to contact us