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Small-molecule based musculoskeletal regenerative engineering

Paper ID Volume ID Publish Year Pages File Format Full-Text
36852 45274 2014 8 PDF Available
Title
Small-molecule based musculoskeletal regenerative engineering
Abstract

•Regenerative engineering has been recently proposed to regenerate complex tissue.•Therapeutic proteins have many limitations for their use in regenerating tissues.•Small-molecule-based therapeutics is emerging as an alternative strategy.•Small molecules may represent the next generation in musculoskeletal regenerative medicine.

Clinicians and scientists working in the field of regenerative engineering are actively investigating a wide range of methods to promote musculoskeletal tissue regeneration. Small-molecule-mediated tissue regeneration is emerging as a promising strategy for regenerating various musculoskeletal tissues and a large number of small-molecule compounds have been recently discovered as potential bioactive molecules for musculoskeletal tissue repair and regeneration. In this review, we summarize the recent literature encompassing the past 4 years in the area of small bioactive molecules for promoting repair and regeneration of various musculoskeletal tissues including bone, muscle, cartilage, tendon, and nerve.

Keywords
tissue regeneration; regenerative engineering; musculoskeletal tissue; small molecules
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Small-molecule based musculoskeletal regenerative engineering
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Publisher
Database: Elsevier - ScienceDirect
Journal: - Volume 32, Issue 2, February 2014, Pages 74–81
Authors
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Subjects
Physical Sciences and Engineering Chemical Engineering Bioengineering
Get Full-Text Now
Don't Miss Today's Special Offer
Price was $35.95
You save - $31
Price after discount Only $4.95
100% Money Back Guarantee
Full-text PDF Download
Online Support
Any Questions? feel free to contact us