fulltext.study @t Gmail

Modularity, context-dependence, and insulation in engineered biological circuits

Paper ID Volume ID Publish Year Pages File Format Full-Text
36909 45282 2015 9 PDF Available
Title
Modularity, context-dependence, and insulation in engineered biological circuits
Abstract

•Insulation of parts and functional modules from their context is a major challenge.•Parts engineering and circuit design are both important in solving context-dependence.

The ability to link systems together such that they behave as predicted once they interact with each other is an essential requirement for the forward-engineering of robust synthetic biological circuits. Unfortunately, because of context-dependencies, parts and functional modules often behave unpredictably once interacting in the cellular environment. This paper reviews recent advances toward establishing a rigorous engineering framework for insulating parts and modules from their context to improve modularity. Overall, a synergy between engineering better parts and higher-level circuit design will be important to resolve the problem of context-dependence.

First Page Preview
Modularity, context-dependence, and insulation in engineered biological circuits
Get Full-Text Now
Don't Miss Today's Special Offer
Price was $35.95
You save - $31
Price after discount Only $4.95
100% Money Back Guarantee
Full-text PDF Download
Online Support
Any Questions? feel free to contact us
Publisher
Database: Elsevier - ScienceDirect
Journal: - Volume 33, Issue 2, February 2015, Pages 111–119
Authors
,
Subjects
Physical Sciences and Engineering Chemical Engineering Bioengineering
Get Full-Text Now
Don't Miss Today's Special Offer
Price was $35.95
You save - $31
Price after discount Only $4.95
100% Money Back Guarantee
Full-text PDF Download
Online Support
Any Questions? feel free to contact us