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Imaging cardiac extracellular matrices: a blueprint for regeneration

Paper ID Volume ID Publish Year Pages File Format Full-Text
36954 45290 2012 8 PDF Available
Title
Imaging cardiac extracellular matrices: a blueprint for regeneration
Abstract

Once damaged, cardiac tissue does not readily repair and is therefore a primary target of regenerative therapies. One regenerative approach is the development of scaffolds that functionally mimic the cardiac extracellular matrix (ECM) to deliver stem cells or cardiac precursor populations to the heart. Technological advances in micro/nanotechnology, stem cell biology, biomaterials and tissue decellularization have propelled this promising approach forward. Surprisingly, technological advances in optical imaging methods have not been fully utilized in the field of cardiac regeneration. Here, we describe and provide examples to demonstrate how advanced imaging techniques could revolutionize how ECM-mimicking cardiac tissues are informed and evaluated.

Keywords
extracellular matrix; developing heart; multimodality imaging; tissue engineering; biomaterials
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Publisher
Database: Elsevier - ScienceDirect
Journal: - Volume 30, Issue 4, April 2012, Pages 233–240
Authors
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Subjects
Physical Sciences and Engineering Chemical Engineering Bioengineering
Get Full-Text Now
Don't Miss Today's Special Offer
Price was $35.95
You save - $31
Price after discount Only $4.95
100% Money Back Guarantee
Full-text PDF Download
Online Support
Any Questions? feel free to contact us