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Promises and pitfalls of synthetic chromosomes in plants

Paper ID Volume ID Publish Year Pages File Format Full-Text
36982 45293 2015 6 PDF Available
Title
Promises and pitfalls of synthetic chromosomes in plants
Abstract

•Minichromosomes in plants can be synthesized by telomere-mediated truncation.•Transgenes can be added to minichromosomes upon their formation.•The epigenetic nature of centromeres precludes their use for plant synthetic chromosomes.•Engineered minichromosomes have the potential to stack numerous genes of interest.

This review summarizes synthetic chromosome construction in plants and speculates on how they might be applied to various uses in the future, as well as the possible impact for synthetic biology. The procedures to construct foundational platforms for synthetic chromosomes in plants are described, together with some challenges to be overcome in growing such chromosomes and expanding their applications.

Keywords
synthetic biology; plants; engineered minichromosomes; artificial chromosomes; food security; centromere; genetic engineering
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Promises and pitfalls of synthetic chromosomes in plants
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Publisher
Database: Elsevier - ScienceDirect
Journal: - Volume 33, Issue 3, March 2015, Pages 189–194
Authors
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Subjects
Physical Sciences and Engineering Chemical Engineering Bioengineering
Get Full-Text Now
Don't Miss Today's Special Offer
Price was $35.95
You save - $31
Price after discount Only $4.95
100% Money Back Guarantee
Full-text PDF Download
Online Support
Any Questions? feel free to contact us