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Advances and perspectives in in vitro human gut fermentation modeling

Paper ID Volume ID Publish Year Pages File Format Full-Text
36997 45295 2012 9 PDF Available
Title
Advances and perspectives in in vitro human gut fermentation modeling
Abstract

The gut microbiota is a highly specialized organ containing host-specific assemblages of microbes whereby metabolic activity directly impacts human health and disease. In vitro gut fermentation models present an unmatched opportunity of performing studies frequently challenged in humans and animals owing to ethical concerns. Multidisciplinary systems biology analyses supported by ‘-omics’ platforms remain widely neglected in the field of in vitro gut fermentation modeling but are key to advancing the significance of these models. Model-driven experimentation using a combination of in vitro gut fermentation and in vitro human cell models represent an advanced approach in identifying complex host–microbe interactions and niches central to gut fermentation processes. The aim of this review is to highlight the advances and challenges exhibited by in vitro human gut fermentation modeling.

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Advances and perspectives in in vitro human gut fermentation modeling
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Publisher
Database: Elsevier - ScienceDirect
Journal: - Volume 30, Issue 1, January 2012, Pages 17–25
Authors
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Subjects
Physical Sciences and Engineering Chemical Engineering Bioengineering
Get Full-Text Now
Don't Miss Today's Special Offer
Price was $35.95
You save - $31
Price after discount Only $4.95
100% Money Back Guarantee
Full-text PDF Download
Online Support
Any Questions? feel free to contact us