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Taking your breath away: metabolomics breathes life in to personalized medicine

Paper ID Volume ID Publish Year Pages File Format Full-Text
37010 45297 2014 11 PDF Available
Title
Taking your breath away: metabolomics breathes life in to personalized medicine
Abstract

•Breathomics is an upcoming bioanalytical area transforming point-of-care diagnostics.•Volatile organic compounds (VOCs) are an important source of potential diagnostic information.•Current technologies bridge the gap from large analytical systems to portable sensor platforms.

Breath-based metabolomics (breathomics) is an exciting developing area of biotechnology that centers on the capture, identification, and quantification of volatile organic compound (VOC) patterns in human breath and their utilization as tools in the diagnosis of a broad spectrum of medical problems. With the age of personalized medicines demanding rapid bespoke diagnosis and treatment, this area of molecular diagnostics is beginning to see an upsurge in biotechnological advancement. Here, we discuss recent improvements and directions in the development of breath VOC analysis and diagnosis platforms that offer the potential for disease biomarker discovery and disease prognosis.

Keywords
breathomics; volatile organic compounds; personalized medicine; point-of-care; eNose; mass spectrometry
First Page Preview
Taking your breath away: metabolomics breathes life in to personalized medicine
Publisher
Database: Elsevier - ScienceDirect
Journal: - Volume 32, Issue 10, October 2014, Pages 538–548
Authors
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Subjects
Physical Sciences and Engineering Chemical Engineering Bioengineering