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Escherichia coli for biofuel production: bridging the gap from promise to practice

Paper ID Volume ID Publish Year Pages File Format Full-Text
37043 45301 2012 8 PDF Available
Title
Escherichia coli for biofuel production: bridging the gap from promise to practice
Abstract

The anticipated shift of biofuel feedstocks from maize to lignocellulose presents challenges in developing effective biomass pretreatment approaches, which impacts the selection and capabilities of fuel-producing organisms. For a viable biofuel production process, the ideal fuel-producing organism must be able to efficiently convert a variety of sugars to fuels anaerobically at near-theoretical yields, resist inhibitors generated by biomass pretreatment and exhibit low product toxicity. Escherichia coli finds extensive use as a model system, but has not been widely used as an industrial host. This review highlights recent advances in metabolic engineering of biofuel-synthesis pathways in E. coli and summarizes insights gained into regulation of those pathways, and describes progress toward overcoming the challenges facing its adoption as a biofuel-production strain.

Keywords
Escherichia coli; biofuels; anaerobic; secretion; phage; lignocellulose
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Escherichia coli for biofuel production: bridging the gap from promise to practice
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Publisher
Database: Elsevier - ScienceDirect
Journal: - Volume 30, Issue 10, October 2012, Pages 538–545
Authors
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Subjects
Physical Sciences and Engineering Chemical Engineering Bioengineering
Get Full-Text Now
Don't Miss Today's Special Offer
Price was $35.95
You save - $31
Price after discount Only $4.95
100% Money Back Guarantee
Full-text PDF Download
Online Support
Any Questions? feel free to contact us