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Recent advances in bone tissue engineering scaffolds

Paper ID Volume ID Publish Year Pages File Format Full-Text
37044 45301 2012 9 PDF Available
Title
Recent advances in bone tissue engineering scaffolds
Abstract

Bone disorders are of significant concern due to increase in the median age of our population. Traditionally, bone grafts have been used to restore damaged bone. Synthetic biomaterials are now being used as bone graft substitutes. These biomaterials were initially selected for structural restoration based on their biomechanical properties. Later scaffolds were engineered to be bioactive or bioresorbable to enhance tissue growth. Now scaffolds are designed to induce bone formation and vascularization. These scaffolds are often porous, made of biodegradable materials that harbor different growth factors, drugs, genes, or stem cells. In this review, we highlight recent advances in bone scaffolds and discuss aspects that still need to be improved.

Keywords
bone scaffolds; biomolecule delivery; osteoinduction; vascularization; biomechanical properties; in vitro and in vivo studies
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Recent advances in bone tissue engineering scaffolds
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Publisher
Database: Elsevier - ScienceDirect
Journal: - Volume 30, Issue 10, October 2012, Pages 546–554
Authors
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Subjects
Physical Sciences and Engineering Chemical Engineering Bioengineering
Get Full-Text Now
Don't Miss Today's Special Offer
Price was $35.95
You save - $31
Price after discount Only $4.95
100% Money Back Guarantee
Full-text PDF Download
Online Support
Any Questions? feel free to contact us