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Virus scaffolds as enzyme nano-carriers

Paper ID Volume ID Publish Year Pages File Format Full-Text
37089 45310 2012 8 PDF Available
Title
Virus scaffolds as enzyme nano-carriers
Abstract

The cooperative organization of enzymes by cells is a key feature for the efficiency of living systems. In the field of nanotechnologies, effort currently aims at mimicking this natural organization. Nanoscale resolution and high-registration alignment are necessary to control enzyme distribution in nano-containers or on the surface of solid supports. Virus capsid self-assembly is driven by precise supramolecular combinations of protein monomers, which have made them attractive building blocks to engineer enzyme nano-carriers (ENCs). We discuss some examples of what in our opinion constitute the latest advances in the use of plant viruses, bacteriophages and virus-like particles (VLPs) as nano-scaffolds for enzyme selection, enzyme confinement and patterning, phage therapy, raw material processing, and single molecule enzyme kinetics studies.

Keywords
enzyme nano-carrier; virus-like particle; virus scaffold; bacteriophage; enzyme selection
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Virus scaffolds as enzyme nano-carriers
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Publisher
Database: Elsevier - ScienceDirect
Journal: - Volume 30, Issue 7, July 2012, Pages 369–376
Authors
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Subjects
Physical Sciences and Engineering Chemical Engineering Bioengineering
Get Full-Text Now
Don't Miss Today's Special Offer
Price was $35.95
You save - $31
Price after discount Only $4.95
100% Money Back Guarantee
Full-text PDF Download
Online Support
Any Questions? feel free to contact us