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Stem cell metabolic and spectroscopic profiling

Paper ID Volume ID Publish Year Pages File Format Full-Text
37128 45313 2013 10 PDF Available
Title
Stem cell metabolic and spectroscopic profiling
Abstract

Stem cells offer great potential for regenerative medicine because they regenerate damaged tissue by cell replacement and/or by stimulating endogenous repair mechanisms. Although stem cells are defined by their functional properties, such as the potential to proliferate, to self-renew, and to differentiate into specific cell types, their identification based on the expression of specific markers remains vague. Here, profiles of stem cell metabolism might highlight stem cell function more than the expression of single genes/markers. Thus, systematic approaches including spectroscopy might yield insight into stem cell function, identity, and stemness. We review the findings gained by means of metabolic and spectroscopic profiling methodologies, for example, nuclear magnetic resonance spectroscopy (NMRS), mass spectrometry (MS), and Raman spectroscopy (RS), with a focus on neural stem cells and neurogenesis.

Keywords
stem cells; metabolomics; NMR spectroscopy; mass spectrometry; Raman microspectroscopy; mobile lipids
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Stem cell metabolic and spectroscopic profiling
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Publisher
Database: Elsevier - ScienceDirect
Journal: - Volume 31, Issue 3, March 2013, Pages 204–213
Authors
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Subjects
Physical Sciences and Engineering Chemical Engineering Bioengineering
Get Full-Text Now
Don't Miss Today's Special Offer
Price was $35.95
You save - $31
Price after discount Only $4.95
100% Money Back Guarantee
Full-text PDF Download
Online Support
Any Questions? feel free to contact us