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Recombinant lactic acid bacteria as mucosal biotherapeutic agents

Paper ID Volume ID Publish Year Pages File Format Full-Text
37133 45314 2011 10 PDF Available
Title
Recombinant lactic acid bacteria as mucosal biotherapeutic agents
Abstract

The safety status of lactic acid bacteria (LAB) and their capacity to survive the passage through the gastrointestinal tract (GI tract) have rendered them excellent candidates for the production of therapeutic proteins and their delivery in situ to the GI tract. During the past two decades, major health benefits of mucosally administered recombinant LAB have been successfully demonstrated, predominantly using animal models. However, the field has recently moved into the era of human clinical trials. In this review, we provide a timely update on the recent important advances made in this field, and outline the potential of recombinant LAB as therapeutic tools for their safe and efficient use in human health.

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Recombinant lactic acid bacteria as mucosal biotherapeutic agents
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Publisher
Database: Elsevier - ScienceDirect
Journal: - Volume 29, Issue 10, October 2011, Pages 499–508
Authors
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Subjects
Physical Sciences and Engineering Chemical Engineering Bioengineering
Get Full-Text Now
Don't Miss Today's Special Offer
Price was $35.95
You save - $31
Price after discount Only $4.95
100% Money Back Guarantee
Full-text PDF Download
Online Support
Any Questions? feel free to contact us