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Single cells as experimentation units in lab-on-a-chip devices

Paper ID Volume ID Publish Year Pages File Format Full-Text
37138 45315 2010 8 PDF Available
Title
Single cells as experimentation units in lab-on-a-chip devices
Abstract

‘Lab-on-a-chip’ technology (LOC) has now reached a mature state and is employed commonly in research in the life sciences. LOC devices make novel experimentation possible while providing a sophisticated environment for cellular investigation. As a next step, we introduce here the concept of a ‘lab-in-a-cell’: the use of a single cell as a minimal and highly confined experimental unit, or experimentation in the simple, but still unequalled, platform provided by nature itself. LOC provides the appropriate format and set of tools for LIC experimentation, and we discuss here three types of LIC investigation: the elucidation of signaling pathways; the creation of novel production units; and the use of microfluidics for assisted reproduction techniques.

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Publisher
Database: Elsevier - ScienceDirect
Journal: - Volume 28, Issue 2, February 2010, Pages 55–62
Authors
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Subjects
Physical Sciences and Engineering Chemical Engineering Bioengineering
Get Full-Text Now
Don't Miss Today's Special Offer
Price was $35.95
You save - $31
Price after discount Only $4.95
100% Money Back Guarantee
Full-text PDF Download
Online Support
Any Questions? feel free to contact us