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Endothelialized biomaterials for tissue engineering applications in vivo

Paper ID Volume ID Publish Year Pages File Format Full-Text
37147 45316 2011 9 PDF Available
Title
Endothelialized biomaterials for tissue engineering applications in vivo
Abstract

Rebuilding tissues involves the creation of a vasculature to supply nutrients and this in turn means that the endothelial cells (ECs) of the resulting endothelium must be a quiescent non-thrombogenic blood contacting surface. Such ECs are deployed on biomaterials that are composed of natural materials such as extracellular matrix proteins or synthetic polymers in the form of vascular grafts or tissue-engineered constructs. Because EC function is influenced by their origin, biomaterial surface chemistry and hemodynamics, these issues must be considered to optimize implant performance. In this review, we examine the recent in vivo use of endothelialized biomaterials and discuss the fundamental issues that must be considered when engineering functional vasculature.

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Endothelialized biomaterials for tissue engineering applications in vivo
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Publisher
Database: Elsevier - ScienceDirect
Journal: - Volume 29, Issue 8, August 2011, Pages 379–387
Authors
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Subjects
Physical Sciences and Engineering Chemical Engineering Bioengineering
Get Full-Text Now
Don't Miss Today's Special Offer
Price was $35.95
You save - $31
Price after discount Only $4.95
100% Money Back Guarantee
Full-text PDF Download
Online Support
Any Questions? feel free to contact us