fulltext.study @t Gmail

Baker's yeast mediated biotransformation of geraniol into citronellol using a continuous-closed-gas-loop bioreactor (CCGLB) system

Paper ID Volume ID Publish Year Pages File Format Full-Text
3719 183 2011 6 PDF Available
Title
Baker's yeast mediated biotransformation of geraniol into citronellol using a continuous-closed-gas-loop bioreactor (CCGLB) system
Abstract

The kinetics of the biotransformation of geraniol into citronellol by the resting cells of Saccharomyces cerevisiae (baker's yeast type-II) was investigated in a continuous-closed-gas-loop bioreactor (CCGLB). Geraniol, which has high vapour pressure, high volatility and low solubility in aqueous medium, is highly suitable to be used in this system. Various operating parameters which affect the reduction reaction were investigated. The optimal conditions were; pH 7, agitation rate of 350 rpm, substrate flow rate of 8 L/min and glucose concentration of 50 g/L. The gas loop led to a maximum citronellol concentration of 2.38 g/L with the specific activity of 7.90 U/gcell, which were apparently higher than that of the values obtained using conventional systems. The CCGLB system also has the advantage of in situ product removal and can be readily utilized in large-scale production.

► The CCGLB system gives an advantage of in situ product removal. ► Gas phase biotransformation promotes better mass transfer between gas and liquid phases. ► High substrate flow rate gives a positive effect to the rate of reaction. ► High agitation leads to an excessive foaming inside the CCGLB.

Keywords
Yeast; Biotransformations; In-situ product removal; Continuous-closed-gas-loop bioreactor (CCGLB); Production kinetics; Heterogeneous biocatalysis
First Page Preview
Baker's yeast mediated biotransformation of geraniol into citronellol using a continuous-closed-gas-loop bioreactor (CCGLB) system
Get Full-Text Now
Don't Miss Today's Special Offer
Price was $35.95
You save - $31
Price after discount Only $4.95
100% Money Back Guarantee
Full-text PDF Download
Online Support
Any Questions? feel free to contact us
Publisher
Database: Elsevier - ScienceDirect
Journal: Biochemical Engineering Journal - Volume 56, Issue 3, 15 October 2011, Pages 219–224
Authors
, , ,
Subjects
Physical Sciences and Engineering Chemical Engineering Bioengineering
Get Full-Text Now
Don't Miss Today's Special Offer
Price was $35.95
You save - $31
Price after discount Only $4.95
100% Money Back Guarantee
Full-text PDF Download
Online Support
Any Questions? feel free to contact us