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19F MRI for quantitative in vivo cell tracking

Paper ID Volume ID Publish Year Pages File Format Full-Text
37217 45324 2010 8 PDF Available
Title
19F MRI for quantitative in vivo cell tracking
Abstract

Cellular therapy, including stem cell transplants and dendritic cell vaccines, is typically monitored for dosage optimization, accurate delivery, and localization using noninvasive imaging, of which magnetic resonance imaging (MRI) is a key modality. 19F MRI retains the advantages of MRI as an imaging modality, and also allows direct detection of labeled cells for unambiguous identification and quantification, unlike typical metal-based contrast agents. Recent developments in 19F MRI-based in vivo cell quantification, the existing clinical use of 19F compounds and current explosive interest in cellular therapeutics have brought 19F imaging technology closer to clinical application. We review the application of 19F MRI to cell tracking, discussing intracellular 19F labels, cell labeling and in vivo quantification, as well as the potential clinical uses of 19F MRI.

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19F MRI for quantitative in vivo cell tracking
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Publisher
Database: Elsevier - ScienceDirect
Journal: - Volume 28, Issue 7, July 2010, Pages 363–370
Authors
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Subjects
Physical Sciences and Engineering Chemical Engineering Bioengineering
Get Full-Text Now
Don't Miss Today's Special Offer
Price was $35.95
You save - $31
Price after discount Only $4.95
100% Money Back Guarantee
Full-text PDF Download
Online Support
Any Questions? feel free to contact us