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Colloidal systems for drug delivery: from design to therapy

Paper ID Volume ID Publish Year Pages File Format Full-Text
37249 45328 2012 12 PDF Available
Title
Colloidal systems for drug delivery: from design to therapy
Abstract

Nanomedicine, or medicine using nanometric devices, has emerged in the past decade as an exhilarating domain that can help to solve a number of problems linked to unsatisfactory therapeutic responses of so-called ‘old drugs’. This dissatisfaction stems from inadequate biodistribution after a drug's application, which leads to a limited therapeutic response but also to numerous side effects to healthy organs. The biodistribution of drugs encapsulated in a nanoobject that will act as a vector can be modified to tune its therapeutic efficacy. This review provides a general overview of existing colloidal nanovectors: liposomes, polymeric micelles, polymeric vesicles, polymeric nanoparticles (NPs), and dendrimers. We describe their characteristics, advantages and drawbacks, and discuss their use in the treatment of various diseases.

Keywords
drug delivery; soft matter; oncology; nanovectors; central nervous system
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Publisher
Database: Elsevier - ScienceDirect
Journal: - Volume 30, Issue 9, September 2012, Pages 485–496
Authors
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Subjects
Physical Sciences and Engineering Chemical Engineering Bioengineering
Get Full-Text Now
Don't Miss Today's Special Offer
Price was $35.95
You save - $31
Price after discount Only $4.95
100% Money Back Guarantee
Full-text PDF Download
Online Support
Any Questions? feel free to contact us