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The importance of engineering physiological functionality into microbes

Paper ID Volume ID Publish Year Pages File Format Full-Text
37252 45329 2009 9 PDF Available
Title
The importance of engineering physiological functionality into microbes
Abstract

Good physiological performance of industrial microbes is crucial for successful bioprocesses. Conventional metabolism-oriented engineering strategies often fail to obtain expected phenotypes owing to focusing narrowly on targeted metabolic capabilities while neglecting microbial physiological responses to environmental stresses. To meet the new challenges posed by the biotechnological production of fuels, chemicals and materials, microbes should exert strong physiological robustness and fitness, in addition to strong metabolic capabilities, to enable them to work efficiently in actual bioprocesses. Here, we address the importance of engineering physiological functionalities into microbes and illustrate the operation procedure. We believe that this physiology-oriented engineering strategy is a promising approach for improving the physiological performance of industrial microbes for efficient bioprocesses.

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Publisher
Database: Elsevier - ScienceDirect
Journal: - Volume 27, Issue 12, December 2009, Pages 664–672
Authors
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Subjects
Physical Sciences and Engineering Chemical Engineering Bioengineering
Get Full-Text Now
Don't Miss Today's Special Offer
Price was $35.95
You save - $31
Price after discount Only $4.95
100% Money Back Guarantee
Full-text PDF Download
Online Support
Any Questions? feel free to contact us