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Acoustic wave biosensors: physical models and biological applications of quartz crystal microbalance

Paper ID Volume ID Publish Year Pages File Format Full-Text
37255 45329 2009 9 PDF Available
Title
Acoustic wave biosensors: physical models and biological applications of quartz crystal microbalance
Abstract

Piezoelectric sensors are acoustic sensors that enable the selective and label-free detection of biological events in real time. These sensors generate acoustic waves and utilize measurements of the variation of the wave propagation properties as a signal for probing events at the sensor surface. Quartz crystal microbalance (QCM) devices, the most widespread acoustic resonators, allow the study of viscoelastic properties of matter, the adsorption of molecules, or the motility of living cells. In a tutorial-like approach, this review addresses the physical principles associated with the QCM, as well as the origin and effects of major interfering phenomena. Special attention is paid to the possibilities offered by QCM that go beyond microweighing, and important recent examples are presented.

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Acoustic wave biosensors: physical models and biological applications of quartz crystal microbalance
Publisher
Database: Elsevier - ScienceDirect
Journal: - Volume 27, Issue 12, December 2009, Pages 689–697
Authors
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Subjects
Physical Sciences and Engineering Chemical Engineering Bioengineering