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Simultaneous co-fermentation of mixed sugars: a promising strategy for producing cellulosic ethanol

Paper ID Volume ID Publish Year Pages File Format Full-Text
37288 45334 2012 9 PDF Available
Title
Simultaneous co-fermentation of mixed sugars: a promising strategy for producing cellulosic ethanol
Abstract

The lack of microbial strains capable of fermenting all sugars prevalent in plant cell wall hydrolyzates to ethanol is a major challenge. Although naturally existing or engineered microorganisms can ferment mixed sugars (glucose, xylose and galactose) in these hydrolyzates sequentially, the preferential utilization of glucose to non-glucose sugars often results in lower overall yield and productivity of ethanol. Therefore, numerous metabolic engineering approaches have been attempted to construct optimal microorganisms capable of co-fermenting mixed sugars simultaneously. Here, we present recent findings and breakthroughs in engineering yeast for improved ethanol production from mixed sugars. In particular, this review discusses new sugar transporters, various strategies for simultaneous co-fermentation of mixed sugars, and potential applications of co-fermentation for producing fuels and chemicals.

Keywords
cellodextrin transporter; intracellular β-glucosidase; glucose repression; cellobiose; xylose; galactose
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Simultaneous co-fermentation of mixed sugars: a promising strategy for producing cellulosic ethanol
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Publisher
Database: Elsevier - ScienceDirect
Journal: - Volume 30, Issue 5, May 2012, Pages 274–282
Authors
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Subjects
Physical Sciences and Engineering Chemical Engineering Bioengineering
Get Full-Text Now
Don't Miss Today's Special Offer
Price was $35.95
You save - $31
Price after discount Only $4.95
100% Money Back Guarantee
Full-text PDF Download
Online Support
Any Questions? feel free to contact us