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Comparing microarrays and next-generation sequencing technologies for microbial ecology research

Paper ID Volume ID Publish Year Pages File Format Full-Text
37293 45335 2010 9 PDF Available
Title
Comparing microarrays and next-generation sequencing technologies for microbial ecology research
Abstract

Recent advances in molecular biology have resulted in the application of DNA microarrays and next-generation sequencing (NGS) technologies to the field of microbial ecology. This review aims to examine the strengths and weaknesses of each of the methodologies, including depth and ease of analysis, throughput and cost-effectiveness. It also intends to highlight the optimal application of each of the individual technologies toward the study of a particular environment and identify potential synergies between the two main technologies, whereby both sample number and coverage can be maximized. We suggest that the efficient use of microarray and NGS technologies will allow researchers to advance the field of microbial ecology, and importantly, improve our understanding of the role of microorganisms in their various environments.

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Comparing microarrays and next-generation sequencing technologies for microbial ecology research
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Publisher
Database: Elsevier - ScienceDirect
Journal: - Volume 28, Issue 6, June 2010, Pages 291–299
Authors
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Subjects
Physical Sciences and Engineering Chemical Engineering Bioengineering
Get Full-Text Now
Don't Miss Today's Special Offer
Price was $35.95
You save - $31
Price after discount Only $4.95
100% Money Back Guarantee
Full-text PDF Download
Online Support
Any Questions? feel free to contact us