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Fiber-optic probes enable cancer detection with FTIR spectroscopy

Paper ID Volume ID Publish Year Pages File Format Full-Text
37296 45335 2010 7 PDF Available
Title
Fiber-optic probes enable cancer detection with FTIR spectroscopy
Abstract

Fourier transform infrared spectroscopy (FTIR) reveals biochemical ‘fingerprints’ and has found disease patterns in excised human tissues. Fiber-optic probes have been developed for FTIR in living systems, allowing for cancer detection. There are challenges to making in vivo FTIR a reality, which are being addressed through hardware advances, determining key wavelengths and tissue preparation. Fiber-optic evanescent wave spectroscopy (FEWS)-FTIR with endoscope-compatible fiber-optic silver halide probes is feasible, and could prove useful for distinguishing premalignant and malignant tissues from biopsies or within patients. Developments of smaller silver halide probes as well as in vivo tissue drying methods will move this approach closer to the clinic where it can be used for early cancer detection, disease characterization and guided biopsies.

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Publisher
Database: Elsevier - ScienceDirect
Journal: - Volume 28, Issue 6, June 2010, Pages 317–323
Authors
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Subjects
Physical Sciences and Engineering Chemical Engineering Bioengineering
Get Full-Text Now
Don't Miss Today's Special Offer
Price was $35.95
You save - $31
Price after discount Only $4.95
100% Money Back Guarantee
Full-text PDF Download
Online Support
Any Questions? feel free to contact us