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Live-imaging fluorescent proteins in mouse embryos: multi-dimensional, multi-spectral perspectives

Paper ID Volume ID Publish Year Pages File Format Full-Text
37333 45341 2009 11 PDF Available
Title
Live-imaging fluorescent proteins in mouse embryos: multi-dimensional, multi-spectral perspectives
Abstract

Microscopy has always been an obligate tool in the field of developmental biology, a goal of which is to elucidate the essential cellular and molecular interactions that coordinate the specification of different cell types and the establishment of body plans. The 2008 Nobel Prize in chemistry was awarded ‘for the discovery and development of the green fluorescent protein, GFP’ in recognition that the discovery of genetically encoded fluorescent proteins (FPs) has spearheaded a revolution in applications for imaging of live cells. With the development of more-sophisticated imaging technology and availability of FPs with different spectral characteristics, dynamic processes can now be live-imaged at high resolution in situ in embryos. Here, we review some recent advances in this rapidly evolving field as applied to live-imaging capabilities in the mouse, the most genetically tractable mammalian model organism for embryologists.

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Live-imaging fluorescent proteins in mouse embryos: multi-dimensional, multi-spectral perspectives
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Publisher
Database: Elsevier - ScienceDirect
Journal: - Volume 27, Issue 5, May 2009, Pages 266–276
Authors
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Subjects
Physical Sciences and Engineering Chemical Engineering Bioengineering
Get Full-Text Now
Don't Miss Today's Special Offer
Price was $35.95
You save - $31
Price after discount Only $4.95
100% Money Back Guarantee
Full-text PDF Download
Online Support
Any Questions? feel free to contact us