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Synthetic biosystems for the production of high-value plant metabolites

Paper ID Volume ID Publish Year Pages File Format Full-Text
37375 45347 2012 5 PDF Available
Title
Synthetic biosystems for the production of high-value plant metabolites
Abstract

Plants display an immense diversity of specialized metabolites, many of which have been important to humanity as medicines, flavors, fragrances, pigments, insecticides and other fine chemicals. Apparently, much of the variation in plant specialized metabolism evolved through events of gene duplications followed by neo- or sub-functionalization. Most of the catalytic diversity of plant enzymes is unexplored since previous biochemical and genomics efforts have focused on a relatively small number of species. Interdisciplinary research in plant genomics, microbial engineering and synthetic biology provides an opportunity to accelerate the discovery of new enzymes. The massive identification, characterization and cataloguing of plant enzymes coupled with their deployment in metabolically optimized microbes provide a high-throughput functional genomics tool and a novel strain engineering pipeline.

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Synthetic biosystems for the production of high-value plant metabolites
Publisher
Database: Elsevier - ScienceDirect
Journal: - Volume 30, Issue 3, March 2012, Pages 127–131
Authors
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Subjects
Physical Sciences and Engineering Chemical Engineering Bioengineering