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Mutasynthesis – uniting chemistry and genetics for drug discovery

Paper ID Volume ID Publish Year Pages File Format Full-Text
37440 45356 2007 4 PDF Available
Title
Mutasynthesis – uniting chemistry and genetics for drug discovery
Abstract

Mutasynthesis couples the power of chemical synthesis with molecular biology to generate derivatives of medicinally valuable, natural products. Recently, this technique has been exploited by Cambridge-based biotech company Biotica Technology Ltd, and their collaborators, to generate promising new variants of the polyketide anti-cancer compounds rapamycin and borrelidin.

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Mutasynthesis – uniting chemistry and genetics for drug discovery
Publisher
Database: Elsevier - ScienceDirect
Journal: - Volume 25, Issue 4, April 2007, Pages 139–142
Authors
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Subjects
Physical Sciences and Engineering Chemical Engineering Bioengineering