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MALDI imaging mass spectrometry of human tissue: method challenges and clinical perspectives

Paper ID Volume ID Publish Year Pages File Format Full-Text
37453 45357 2011 8 PDF Available
Title
MALDI imaging mass spectrometry of human tissue: method challenges and clinical perspectives
Abstract

The molecular complexity of biological tissue and the spatial and temporal variation in the biological processes involved in human disease requires new technologies and new approaches to provide insight into disease processes. Imaging mass spectrometry is an effective tool that provides molecular images of tissues in the molecular discovery process. The analysis of human tissue presents special challenges and limitations because the heterogeneity among human tissues and diseases is much greater than that observed in animal models, and discoveries made in animal tissues might not translate well to their human counterparts. In this article, we briefly review the challenges of imaging human tissue using mass spectrometry and suggest approaches to address these issues.

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MALDI imaging mass spectrometry of human tissue: method challenges and clinical perspectives
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Publisher
Database: Elsevier - ScienceDirect
Journal: - Volume 29, Issue 3, March 2011, Pages 136–143
Authors
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Subjects
Physical Sciences and Engineering Chemical Engineering Bioengineering
Get Full-Text Now
Don't Miss Today's Special Offer
Price was $35.95
You save - $31
Price after discount Only $4.95
100% Money Back Guarantee
Full-text PDF Download
Online Support
Any Questions? feel free to contact us