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Design and application of genetically encoded biosensors

Paper ID Volume ID Publish Year Pages File Format Full-Text
37454 45357 2011 9 PDF Available
Title
Design and application of genetically encoded biosensors
Abstract

In the past 5–10 years, the power of the green fluorescent protein (GFP) and its numerous derivatives has been harnessed toward the development of genetically encoded fluorescent biosensors. These sensors are incorporated into cells or organisms as plasmid DNA, which leads the transcriptional and translational machinery of the cell to express a functional sensor. To date, over 100 different genetically encoded biosensors have been developed for targets as diverse as ions, molecules and enzymes. Such sensors are instrumental in providing a window into the real-time biochemistry of living cells and whole organisms, and are providing unprecedented insight into the inner workings of a cell.

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Design and application of genetically encoded biosensors
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Publisher
Database: Elsevier - ScienceDirect
Journal: - Volume 29, Issue 3, March 2011, Pages 144–152
Authors
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Subjects
Physical Sciences and Engineering Chemical Engineering Bioengineering
Get Full-Text Now
Don't Miss Today's Special Offer
Price was $35.95
You save - $31
Price after discount Only $4.95
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