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Polyblend nanofibers for biomedical applications: perspectives and challenges

Paper ID Volume ID Publish Year Pages File Format Full-Text
37460 45358 2010 9 PDF Available
Title
Polyblend nanofibers for biomedical applications: perspectives and challenges
Abstract

Advances in disease treatment and tissue regeneration are buoyed by new, multifaceted materials that emulate and coercively interact with the local microenvironment. Polyblend nanofibers represent an emerging class of biomimetic nanostructures that can act as proxies of the native tissue, while providing topographical and biochemical cues that promote healing. These fibers are prepared with mixtures of synthetically and naturally derived polymers that can behave cooperatively to demonstrate unique combinations of mechanical, biochemical and structural properties. This flexibility has led to the application of polyblend nanofibers in a wide assortment of tissue engineering and drug delivery systems. In this review, we will examine design criteria and properties of polymer-blend nanofibers and their use in tissue engineering and local therapeutic delivery applications.

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Polyblend nanofibers for biomedical applications: perspectives and challenges
Publisher
Database: Elsevier - ScienceDirect
Journal: - Volume 28, Issue 4, April 2010, Pages 189–197
Authors
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Subjects
Physical Sciences and Engineering Chemical Engineering Bioengineering