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Switching cell fate: the remarkable rise of induced pluripotent stem cells and lineage reprogramming technologies

Paper ID Volume ID Publish Year Pages File Format Full-Text
37463 45358 2010 10 PDF Available
Title
Switching cell fate: the remarkable rise of induced pluripotent stem cells and lineage reprogramming technologies
Abstract

Cell reprogramming, in which a differentiated cell is made to switch its fate, is an emerging field with revolutionary prospects in biotechnology and medicine. The recent discovery of induced pluripotency by means of in vitro reprogramming has made way for unprecedented approaches for regenerative medicine, understanding human disease and drug discovery. Moreover, recent studies on regeneration and repair by direct lineage reprogramming in vivo offer an attractive novel alternative to cell therapy. Although we continue to push the limits of current knowledge in the field of cell reprogramming, the mechanistic elements that underlie these processes remain largely elusive. This article reviews landmark developments in cell reprogramming, current knowledge, and technological developments now on the horizon with significant promise for biomedical applications.

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Switching cell fate: the remarkable rise of induced pluripotent stem cells and lineage reprogramming technologies
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Publisher
Database: Elsevier - ScienceDirect
Journal: - Volume 28, Issue 4, April 2010, Pages 214–223
Authors
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Subjects
Physical Sciences and Engineering Chemical Engineering Bioengineering
Get Full-Text Now
Don't Miss Today's Special Offer
Price was $35.95
You save - $31
Price after discount Only $4.95
100% Money Back Guarantee
Full-text PDF Download
Online Support
Any Questions? feel free to contact us